How Second Look Turns Trial Eligibility Rules Into Your Shortlist of Matches
Clinical trials have strict inclusion and exclusion criteria. Second Look applies them automatically to your profile, so you see only trials you're likely eligible for.
Here's Exactly What Happens
Build Your Profile
Tell us about your specific cancer. We don't just ask for "Stage IV"—we ask the questions that actually determine eligibility: location preferences, prior treatments, MSS vs MSI-H status, key biomarkers (KRAS, BRAF), and physical ability (ECOG score).
We Filter Out the Noise
Our system instantly reads the inclusion/exclusion criteria of 2,000+ active trials. We remove trials that require you to be "treatment naive" or exclude your specific mutation—before you ever see them.
2,000+
CRC Trials
~20-50*
Your Matches
*This number varies based on your location preferences and profile details.
Get a Ranked, Plain-English List
Receive a dashboard of trials ranked by match strength. Each trial shows clear "why this matches" explanations. Download a PDF report to discuss with your oncologist.
What You Need to Get Started
You don't need your full medical history, but having these helps:
Diagnosis Details
Stage & Location (e.g., Colon vs. Rectum, Left vs. Right)
Biomarker Status
Do you know if you're MSS or MSI-H? KRAS mutant or wild-type?
Treatment History
Names of chemotherapies you've had (e.g., FOLFOX, FOLFIRI)
Don't know these? That's okay. You can select "I don't know" and update it later.
Your Data Stays Yours
Privacy is built into our design
You Make Contact
Trial sites only hear from you if you choose to reach out
Encrypted Profile
Your profile is encrypted and used only to calculate matches
Never Sold
Your data is never sold—only anonymized stats may improve our platform
Important Limitations
- We are not medical advice. Always consult your oncologist.
- We cannot guarantee enrollment—only the trial site can do that.
- We do not schedule appointments for you.
- Eligibility criteria can change. Always confirm with the trial site.
Ready to Find Your Options?
Create your profile in ~5 minutes and see trials that match your situation.