Free for Colorectal Cancer Patients

    Most Clinical Trials Don't Apply to You.We Find the Ones That Do.

    Second Look filters colorectal cancer trials based on your exact diagnosis, treatment history, and biomarkers — so you only review real options. Built by a Stage IV patient.

    Your Matches

    2,000
    Location: New York State
    Stage IV (Metastatic)
    2 Lines: FOLFOX + FOLFIRI
    Microsatellite Status: MSS
    Biomarker: KRAS G12D

    Your Matches

    22 Trials

    Ready to review

    Exclusively for CRC

    Optimized for Colorectal Cancer

    Patient-Led

    Built by a Stage IV patient

    Completely Free

    No hidden costs for patients

    Privacy First

    Data is encrypted and never sold

    The Only Engine Built on Colorectal Cancer Logic

    We parse the fine print so you don't waste time on trials that exclude you.

    The Basics

    Location / Distance
    Others
    SLC
    Cancer Stage (I, II, III, IV)
    Others
    SLC
    Recruitment Status
    Others
    SLC
    Trial Phase
    Others
    SLC
    Study Type
    Others
    SLC

    The Second Look Advantage

    Multi-Location Search (up to 5 provinces/states or countries)
    Others
    SLC
    Number of Prior Lines of Systemic Therapy (Chemo / Immunotherapy)
    Others
    SLC
    MSS vs MSI-H Status
    Others
    SLC
    All CRC Targetable Biomarkers (KRAS, BRAF, HER2, NRAS, PIK3CA, and more)
    Others
    SLC
    ECOG Performance Score (physical ability score)
    Others
    SLC
    Brain Metastases Status
    Others
    SLC

    + And more: Second Look also filters by primary tumor location, metastatic sites, and additional criteria to help you find the best-fitting trials.

    Founder Story

    Dill, founder of Second Look Cancer

    I'm Dill, a Stage IV colorectal cancer patient who built Second Look Cancer to make it easier for patients to find and understand clinical trials.

    When I was diagnosed at 30, I knew I wanted to do something meaningful in the cancer space — something that could genuinely help others quickly find clinical trials tailored to their diagnosis and treatment history. That's what Second Look Cancer is all about.

    Not Ready to Search? Get Informed First.

    Clinical trials are complex. We translated the medical jargon into a plain-English guide to help you navigate your options.

    What do Phase 1, 2, and 3 mean?

    Understand the difference between safety testing (Phase 1) and comparing against standard of care (Phase 3).

    Will I get a placebo?

    Busting the myths: why most cancer trials give you at least the standard of care, not a sugar pill.

    Questions for your Oncologist

    A checklist of exactly what to ask your care team when discussing trial options.

    Frequently Asked Questions

    Ready to Find Your Match?

    It takes about 5 minutes to build your profile and see trials you actually qualify for.

    Second Look Cancer
    Free for patients
    Privacy-first
    Built by a CRC patient