Second Look filters colorectal cancer trials based on your exact diagnosis, treatment history, and biomarkers — so you only review real options. Built by a Stage IV patient.
Your Matches
Your Matches
22 Trials
Ready to review
Exclusively for CRC
Optimized for Colorectal Cancer
Patient-Led
Built by a Stage IV patient
Completely Free
No hidden costs for patients
Privacy First
Data is encrypted and never sold
We parse the fine print so you don't waste time on trials that exclude you.
| Filter | ClinicalTrials.gov & other trial finders | Second Look |
|---|---|---|
| The Basics | ||
| Location / Distance | ||
| Cancer Stage (I, II, III, IV) | ||
| Recruitment Status | ||
| Trial Phase | ||
| Study Type | ||
| The Second Look Advantage | ||
| Multi-Location Search (up to 5 provinces/states or countries) | ||
| Number of Prior Lines of Systemic Therapy (Chemo / Immunotherapy) | ||
| MSS vs MSI-H Status | ||
| All CRC Targetable Biomarkers (KRAS, BRAF, HER2, NRAS, PIK3CA, and more) | ||
| ECOG Performance Score (physical ability score) | ||
| Brain Metastases Status | ||
+ And more: Second Look also filters by primary tumor location, metastatic sites, and additional criteria to help you find the best-fitting trials.

I'm Dill, a Stage IV colorectal cancer patient who built Second Look Cancer to make it easier for patients to find and understand clinical trials.
When I was diagnosed at 30, I knew I wanted to do something meaningful in the cancer space — something that could genuinely help others quickly find clinical trials tailored to their diagnosis and treatment history. That's what Second Look Cancer is all about.
Clinical trials are complex. We translated the medical jargon into a plain-English guide to help you navigate your options.
Understand the difference between safety testing (Phase 1) and comparing against standard of care (Phase 3).
Busting the myths: why most cancer trials give you at least the standard of care, not a sugar pill.
A checklist of exactly what to ask your care team when discussing trial options.
It takes about 5 minutes to build your profile and see trials you actually qualify for.
